The 19-year-old has missed Argyle's past three games with an ankle injury but is set to return should he come through a training session on Friday.
Speaking about Mason's impending return, Plymouth coach Adam Sadler said: "Everybody connected to the club - players, fans, staff - all know the talent and the ability of Joe.
"He's a real handful, has got loads of potential and will grow into a fantastic footballer, so it gives everybody a lift to see someone of Joe's quality come back into the reckoning."
Plymouth manager Peter Reid has no new injury concerns to contend with following Tuesday's 1-0 defeat at Yeovil, although Onismor Bhasera (knee) and Jim Paterson (personal reasons) remain sidelined.
Yala Bolaise will also miss the Griffin Park encounter after picking up a late red card at Huish Park.
Source: PA
Source: PA