Defender Chris Morgan will return for Sheffield United after a rib injury, but Marcel Seip cannot play under the terms of his loan from Plymouth.Darius Henderson is banned, while James Harper, Ryan France, Kyle Bartley, Toni Kallio, Nick Montgomery, Lee Williamson and Jamie Ward all face fitness tests.
Plymouth defenders Reda Johnson (leg) and Gary Sawyer (knee) will also need to be assessed ahead of the game.
But David McNamee is back in contention after overcoming a groin problem.
MATCH PREVIEW
Plymouth have been beaten on eight of their last nine visits to Sheffield United and can ill afford to leave empty handed this time around. Argyle are one off the bottom of the table - five points from safety - and badly need to pick up points.
The Pilgrims have won only one of the last five matches and four of the 12 league games since Paul Mariner took over as boss. That kind of form is unlikely to keep them up.
And United's form needs to improve if they are to reach the play-offs for the second successive season. Kevin Blackwell's side, who are eighth, have won only one of their last six matches.
But their home record is excellent and sums up the task facing their struggling opponents. Only high-flying Newcastle and Cardiff have won at Bramall Lane this season - both by a single goal.
MATCH FACTS
Head-to-head
• Sheffield United are unbeaten in their last four matches against Plymouth.
Have your say on this match
• United are hoping to do the double over the Pilgrims for the first time since 1983/84, when they were both in the old Third Division.
• Plymouth have won only one of their last 16 matches at Bramall Lane.
Sheffield United
• United are looking to complete their third league double of the season, having already beaten Bristol City and Reading both home and away.
• If on the field from the outset, Andy Taylor will be making his 100th career league start, and Stephen Quinn his 150th.
Plymouth
• Plymouth have lost more Championship games this season by a single goal than any other club (11 of 18).
• Argyle are the only club not to have conceded more than three goals in a Championship game this season.
• The next goal they let in will be the 5,000th conceded in their 90-year Football League history.
MOST RECENT MEETING
Plymouth 0-1 Sheff Utd (5 December 2009)
Sheffield United scorer: Harper 88.
Source: BBC Sport
Source: BBC Sport